![](/__local/A/2F/CA/0A82E59EFC3A833AAA6B6A1346D_245B0E41_21E22.jpg)
陈梦丽,女,博士,特设副教授,硕士生导师。2017年获浙江大学农药学博士学位,2021年2月入职于浙江农林大学立博体育亚洲官网手机版,主要从事杀虫剂神经毒理学、杀虫剂抗性和害虫化学生态学研究。
科研项目:
除虫菊素对白纹伊蚊驱避作用的分子机制研究,国家基金青年科学基金项目,主持。
天然除虫菊素的靶标作用机理研究,中国博士后科学基金,主持。
伊蚊钠离子通道的结构与功能研究,学校科研发展基金,主持。
新烟碱类农药宽谱抗体的识别机制与亲和力调控研究,国家自然科学基金面上项目,参与。
学术论文:
1.Leucine to tryptophane substitution in the pore helix IIP1 confer sodium channel resistance to pyrethroids and DDT. Huiming Wu, Jiali Qian, Zhanyi Xu, Ru Yan, Guonian Zhu, Shaoying Wu*, Mengli Chen*. Pesticide Biochemistry and Physiology, 2023, 105490.
2.Ru Yan, Zhanyi Xu, Jiali Qian, Qiaoling Zhou, Huiming Wu, Yahui Liu, Yirong Guo, Guonian Zhu, Mengli Chen*; Molecular and functional characterization of a conserved odorant receptor from Aedes albopictus, Parasites & Vectors 2022, 15: 43.
3.Dongping Chen, Ru Yan, Zhanyi Xu, Jiali Qian, Yinfang Yu, Shunshun Zhu, Huiming Wu, Guonian Zhu, Mengli Chen*. Silencing of dre4 Contributes to Mortality of Phyllotreta striolata[J]. Insects 2022, 13(11): 1072.
4.Zhanyi Xu, Ru Yan, Jiali Qian, Dongping Chen, Yirong Guo, Guonian Zhu, Huiming Wu, Mengli Chen*. RNAi‐mediated knockdown of juvenile hormone esterase causes mortality and malformation in Tribolium castaneum. Entomological Research 2022, 52(11): 476-482.
5.周巧玲, 徐展益, 鄢茹, 朱国念, 陈梦丽*. 两种挥发性拟除虫菊酯杀虫剂对伊蚊的驱避作用研究. 中国生物防治学报, 2022, 38(1), 215.
6.Ru Yan, Qiaoling Zhou, Zhanyi Xu, Yuyan Wu, Guonian Zhu, Mengceng Wang, Yirong Guo, Ke Dong*, Mengli Chen*. Pyrethrins elicit olfactory response and spatial repellency in Aedes albopictus. Pest Management Science 2021, 77: 3706-3712.
7.Feng Liu#, Qiang Wang#, Peng Xu#, Felipe Andreazza#, Wilson R. Valbon#, Elizabeth Bandason, Mengli Chen, Ru Yan, Bo Feng, Leticia B. Smith, Jeffrey G. Scott, Genki Takamatsu, Makoto Ihara, Kazuhiko Matsuda, James Klimavicz, Joel Coats, Eugenio E. Oliveira, Yuzhe Du, Ke Dong*. A dual-target molecular mechanism of pyrethrum repellency against mosquitoes. Nature Communications 2021,12:2553.
8.Qiang Wang#, Peng Xu#, Felipe Andreazza#, Yahui Liu#, Yoshiko Nomura, Phil Duran, Lan Jiang, Mengli Chen, Genki Takamatsu, Makoto Ihara, Kazuhiko Matsuda, Rufus Isaacs, Eugenio E. Oliveira, Yuzhe Du, Ke Dong*.Identification of multiple odorant receptors essential for pyrethrum repellency in Drosophila melanogaster. PLoS Genetics 2021, 17(7): e1009677.
9.Felipe Andreazza#, Wilson R. Valbon#, Qiang Wang#, Feng Liu, Peng Xu, Elizabeth Bandason, Mengli Chen, Shaoying Wu, Leticia B. Smith, Jeffrey G. Scott, Youfa Jiang, Dingxin Jiang, Aijun Zhang,Eugenio E. Oliveira, Ke Dong*. Sodium channel activation underlies transfluthrin repellency in Aedes aegypti. PLoS Neglected Tropical Disease 2021, 15(7): e0009546.
10.Ru Yan, Qiaoling Zhou, Zhanyi Xu, Guonian Zhu, Ke Dong, Boris S. Zhorov, Mengli Chen*. Three sodium channel mutations from Aedes albopictus confer resistance to Type I, but not Type II pyrethroids. Insect Biochemistry and Molecular Biology. Insect Biochemistry and Molecular Biology 2020, 123.
11.Mengli Chen, Yuzhe Du, Yoshiko Nomura, Boris S. Zhorov and Ke Dong*. Chronology of sodium channel mutations associated with pyrethroid resistance in Aedes aegypti. Archives of Insect Biochemistry & Physiology 2020, 104, e21686.
12.Dandan Xiang, Xiaojun Xu, Qiaoling Zhou, Ru Yan, Mengli Chen*, Yirong Guo, Guonian Zhu. The Expression of Soluble Functionalα7-Nicotinic Acetylcholine Receptors In E. Coli and its High-Affinity Binding to Neonicotinoid Pesticides. Pesticide Biochemistry and Physiology 2020, (164) 237-241, IF 3.402.
13.Zhang, kun#; Chen, Mengli#; Wang, Hao; Deng, denghui; Wang, Qiang; Duan, Wenbo; Bandason, Elizabeth; Wu, shaoying*. Molecular characterization and functional expression of voltage-gated sodium channel variants in Apolygus lucorum (Meyer-Dür). Pest Management Science 2020, (76) 2095-2104.
14.Pengyan Liu, Yuanhao Guo, Shaosha Jiao, Yunyun Chang, Liu Ying, Rubing Zou, Yihua Liu, Mengli Chen, Yirong Guo*, Guonian Zhu. Characterization of variable region genes and discovery of key recognition sites in the complementarity determining regions of the anti-thiacloprid monoclonal antibody. International Journal of Molecular Sciences 2020, 21(18), 6857.
15.Mengli Chen, Yuzhe Du, Shaoying Wu, Yoshiko Nomura, Guonian Zhu, Boris S. Zhorov, Ke Dong*. Molecular evidence of sequential evolution of DDT- and pyrethroid-resistant sodium channel in Aedes aegypti. Plos neglected tropical diseases 2019,1-21.
16.Yanbing Wei, Ru Yan, Qiaoling Zhou, Liya Qiao, Guonian Zhu, Mengli Chen*. Monitoring and mechanisms of chlorantraniliprole resistance in Chilo suppressalis (Lepidoptera: Crambidae) in China. Journal of Economic Entomology 2019, 1-6.
17.谢烽, 林婷, 胡斌, 朱瞬瞬, 陈梦丽, 乔丽雅, 朱国念*. 硬脂酸改性苏云金杆菌伴孢晶体蛋白对其抗紫外线作用及杀虫活性的影响. 浙江农业科学, 2019, 60(8), 1470.
18.Hongcui Liu, Qiong Wu, Tianyi Chu, Yinyuan Mo*, Shuyang Cai, Mengli Chen*, Guonian Zhu. High-dose acute exposure of paraquat induces injuries of swim bladder, gastrointestinal tract and liver via neutrophil-mediated ROS in zebrafish and their relevance for human health risk assessment. Chemosphere 2018, (205) 662-673.
19.Mengli Chen, Yuzhe Du, Guonian Zhu, Genki Takamatsu, Makoto Ihara, Kazuhiko Matsuda, Boris S. Zhorov, Ke Dong*. Action of six pyrethrins purified from the botanical insecticide pyrethrum on cockroach sodium channels expressed in Xenopus oocytes. Pesticide Biochemistry and Physiology 2018, (151) 82-89.
20.Mengli Chen, Yuzhe Du, Yoshiko Nomura, Guonian Zhu, Boris S. Zhorov and Ke Dong*. Mutations of two acidic residues at the cytoplasmic end of segment IIIS6 of an insect sodium channel have distinct effects on pyrethroid Resistance. Insect Biochemistry and Molecular Biology 2017, (82) 1-10.
21.Mengli Chen, Yuzhe Du, Yoshiko Nomura, Guonian Zhu, Boris S. Zhorov and Ke Dong*. Alanine to valine substitutions in the pore helix IIIP1 and linker-helix IIIL45 confer cockroach sodium channel resistance to DDT and pyrethroids. Neurotoxicology 2017, (60) 197-206.
22.Liang Yu, Mengli Chen, Yihua Liu, Wenjun Gui, Guonian Zhu*. Thyroid endocrine disruption in zebrafish larvae following exposure to hexaconazole and tebuconazole. Aquatic Toxicology 2013, 138, 35-42.
23.付岩, 林婷, 陈梦丽, 桂文君, 朱国念*. 烯啶虫胺在柑橘和土壤中的残留及消解动态. 农药学学报, 2012, 14(4), 423-428.
联系方式:
cmlmeng@zafu.edu.cn